Nexodyn AOS AcidOxidizing Solution by APR.ch is the first active Wound Management cleanser

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In no event APR Applied Pharma Research s.a. and its affiliates companies shall be liable for any use or exploitation of the information contained in the following pages if not previously authorized in writing by APR Applied Pharma Research s.a.

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STOP STALLING
RESTART HEALING

Nexodyn® AcidOxidizing Solution (AOS) is the Tehclo™ based wound care solution proven to restart healing in stalled wounds.^2,6 A wealth of evidence and real-world experience consistently show accelerated closure¹ with reduced infection rates¹ and less wound-associated pain². So make Nexodyn® AOS a fundamental part of your wound bed preparation routine.

THE RIGHT ANSWER TO CHRONIC WOUND CHALLENGE

A wealth of evidence and real-world experience consistently show that Nexodyn® AOS reduces healing time, protects from risk of infection, reduces clinical signs of local infection and wound associated pain with a highly tolerable profile.^1,2,6

Adding Nexodyn® AOS to the standard of care for diabetic foot ulcers results in faster healing time and protection from risk of infection¹

Significantly faster healing time⁽¹⁾

Significant protection from risk of infection⁽¹⁾

Nexodyn® AOS reduces clinical signs of local infection and wound-associated pain in leg ulcers²

Significantly reduced clinical signs of local infection⁽²⁾

Significantly reduced wound-associated pain⁽²⁾

Nexodyn® AOS is well tolerated. No adverse events associated with the use of Nexodyn® AOS were reported in any of the listed studies.^1,2,6

TEHCLO™: THE NANOTECHNOLOGY BEHIND NEXODYN® AOS^3,4

Tehclo™ is the APR proprietary global patented nanotechnology platform that applies nanoscience to the production of a unique hypochlorous acid (HClO) solution.
Hypochlorous acid is well-known as a broad-spectrum, fast acting antimicrobial agent naturally produced by neutrophils as part of the innate immune system's response to infections.

Unique combination of 3 physicochemical properties

NEXODYN® AOS IN PRACTICE

Nexodyn® AOS is a sprayable solution for Wound Care with ancillary antimicrobial properties intended for use in the debridement, irrigation, cleansing and moistening of chronic wounds and acute wounds, post-surgical wounds, cuts, abrasions, burns and other lesions.⁵

Nexodyn® AOS is a high-tech innovative product - effective, safe and easy to use in wound care ^1,2,6

The product is certified in EU as Class III Medical Device.

References:

Iacopi E. et al. The Use of a Novel Super-Oxidized Solution on Top of Standard Treatment in the Home Care Management of Postsurgical Lesions of the Diabetic Foot Reduces Reinfections and Shortens Healing Time. Int J Low Extrem Wounds. 2018 Dec; 17(4):268-274
Strohal R, et al. The management of critically colonized and locally infected leg ulcers with an Acid-Oxidizing Solution: A pilot study. Adv Skin Wound Care 31(4):163-171, 2018.
Rani SA, Hoon R, Najafi RR, Khosrovi B, Wang L, Debabov D. The in vitro antimicrobial activity of wound and skin cleansers at nontoxic concentrations. Advances in skin & wound care. 2014;27:65-69.
Woods CG, Fu J, Xue P, et al. Dose-dependent transitions in Nrf2-mediated adaptive response and related stress responses to hypochlorous acid in mouse macrophages. Toxicology and applied pharmacology. 2009;238:27-36.
Nexodyn® AcidOxidizing Solution (AOS) [package insert]. Balerna, Switzerland: APR, Applied Pharma Research SA; 2015.
Ricci E, et al. The management of chronic ulcers with an AcidOxidizing Solution. J Wound Care 25(8):443-50, 2016.