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Holding website  

  • About Us
    • What we do
      • Strategic Approach
    • Management Team
    • Collaboration & Partnering
    • Investors
    • Careers
      • Open Positions
        • Head of Medical Affairs
    • Privacy
  • APR Products
    • Prescription Healthcare Products
      • PKU GOLIKE® Family
      • Nexodyn® – Advanced Wound Care
        • Tehclo Technology
      • Diclofenac Immediate Release
        • Immediate Release Technology
        • Diclofenac 50 mg products
      • Ondansetron ODF
        • ODF Technology
        • Ondansetron ODF products
      • APR TD011 – Epidermolysis Bullosa
        • Tehclo Technology
      • APR TD012 – Hailey Hailey Disease
        • Tehclo Technology
      • APR 1204 – Ocular Surface Diseases
        • Tehclo Technology
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        • Tehclo Technology
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        • Diclofenac 25 mg products
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      • Pediatric
        • Halykoo
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        • What is PKU (Phenylketonuria)?
      • Advanced Wound Care
        • Unmet Medical Need
      • Cancer Supportive Care
        • Nausea and vomiting
        • Oncodermatology
      • CNS (migraine)
      • Rare Dermatological Diseases
        • Epidermolysis Bullosa
        • Hailey Hailey Disease
      • Eye laser surgery
    • Pipeline
  • Our Services
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      • Oral Pharmaceuticals
        • Integrated project development
        • Project design planning
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        • Integrated project development
        • Project design planning
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        • Integrated project development
        • Project design planning
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        • Project design planning
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PKU GOLIKE: the evolution in the nutritional management for Phenylketonuria

PKU GOLIKE is a brand-new product line of food for special medical purposes (FSMP) for a real change in the dietary management of Phenylketonuria (PKU)
PKU GOLIKE consists in a Phe-free amino acid mix in coated granules, developed by applying a patented pharmaceutical technology, the Physiomimic Technology™, to an FSMP.
With the ambition of improving health and quality of life of people living and dealing with PKU the coated granules provide PKU GOLIKE with unique benefits:
  • Better Compliance to the treatment: the granules' special coating masks amino acids' unpleased taste and odour, preventing aftertaste and maintaining the original flavour of food.1
  • Better Metabolic Management and Phe levels control: the coating allows a gradual and prolonged release of amino acids over time, leading to a more physiological absorption in the direction of natural proteins (meat, fish, eggs).1,2,3
PKU GOLIKE
The innovation and benefits of PKU GOLIKE products lie in the granule formulation, which is the basis of all the options in the PKU GOLIKE family.

The granules make PKU GOLIKE different from all other PKU products, which generally dissolve in water.

It can take time to get used to a different format and texture, but it is right because granules remain intact during consumption that you don’t perceive the amino acid taste, odour or aftertaste. Granules break down gradually only during digestion allowing a prolonged release of amino acids and a more physiological absorption in line with natural proteins.1,2
Granules PKU GOLIKE
There are many creative ways to consume the granules. Discover a few here!

The PKU GOLIKE Family: all the products for PKU nutritional management

The PKU GOLIKE range consists of different formats to satisfy PKU patients’ needs.
Discover all!
  • PKU GOLIKE Plus: granules come in sachets with 15g. or 20g. of Protein Equivalents (PE.). Two different formats according to age.
    Discover more about PKU GOLIKE Plus.

    PKU GOLIKE Plus
  • PKU GOLIKE KRUNCH: The new protein substitute to chew! Granules are compressed in tablets to chew. Each tablet contains 1g of P.E.
    Discover more about PKU GOLIKE KRUNCH.

    PKU GOLIKE KRUNCH
  • PKU GOLIKE BAR: The next-generation amino acid mix, developed with patients for patients! Granules lie between the pieces of fruit. The product is available in different flavours and formats (5g and 10g P.E.).
    Discover more about PKU GOLIKE BAR.

    PKU GOLIKE BAR
Please refer to your doctor or your medical centre to discuss daily doses, depending on age, bodyweight, medical condition and any special conditions (e.g. pregnancy and breastfeeding).

PKU GOLIKE products must be used under medical supervision.
References:
  1. Scheinin M, et al. Amino acid plasma profiles from a prolonged-release protein substitute for phenylketonuria: a randomised, single-dose, four-way crossover trial in healthy volunteers. Nutrients. 2020;12(6):1653.
  2. Giarratana N et al. A New Phe-Free Protein Substitute Engineered to Allow a Physiological Absorption of Free Amino Acids for Phenylketonuria. 2018. Journal of Inborn Errors of Metabolism & Screening.
  3. Daly A, et al. Protein substitutes in PKU; their historical evolution. Nutrients. 2021;13(2):484.
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